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File and Folder Locker

File and Folder Locker is a Free and Portable File and Folder Locking Tool Encryption Tool created by Al Emran Tareq. It can be used to encrypt and password protect files and or folders on your USB Flash Drive Lock Files on USB or any other NTFS Formatted Drive. The File and Folder Locker requires no installation on a PC. It can be run directly from the USB Device.
Omziff - Portable Encryption Tool

Omziff is a Free Portable File Encryption Tool that enables you to encrypt and decrypt text-based files using a wide variety of cryptographic algorithms. This lightweight utility also features password generation, file splitting, and secure file deletion, making it a versatile tool for privacy-conscious users. No installation is required, simply run it from your USB flash drive.
TrueCrypt - Disk Data Encryption Software

USB Encryption with TrueCrypt – Portable Data Protection: Need a reliable way to encrypt your sensitive data on USB drives or external storage? This open source disk encryption software that allows you to securely encrypt files and folders on USB flash drives, portable storage devices, and hard disk partitions. Designed for on the go security, TrueCrypt supports traveler mode, meaning it can be launched directly from your USB drive without installation on the host system.
LockNote - Password Encrypted Notes

LockNote is a simple and secure portable text editor that allows users to password-protect their notes and text files using strong AES 256-bit encryption. Whether you want to create new encrypted documents or secure existing text files by dragging and dropping them into the software, this utility makes it easy to keep your sensitive information safe and private.
Ideal for storing confidential information such as passwords, personal notes, or private messages, it combines the convenience of a lightweight notepad with powerful encryption technology. Its straightforward interface requires no installation, making it perfect for use on USB drives or as a portable app.